From 2000 until 2004, Kirsty Gallacher hosted the Sky1 show Kirsty’s Home Videos, a satellite equivalent of ITV’s You’ve Been Framed! in which viewers send in home videos to be screened. In 2002, she presented the morning show RI:SE, and in 2004 began the show Simply the Best. Kirsty Gallacher presented the All Star Cup on Sky1 in 2005 and on ITV in 2006. She has made guest appearances on They Think It’s All Over and A Question of Sport. Kirsty Gallacher presented Ant vs Dec the popular strand on Ant & Dec’s Saturday Night Takeaway.
In 2005, Kirsty Gallacher won the third series of the popular Channel 4 reality television series The Games. She then presented the following years alongside Jamie Theakston. In December 2005, she released a DVD entitled Body Sculpt with Kirsty Gallacher in which she shows a variety of workouts. In July 2006, she co-presented the BBC reality TV show Only Fools on Horses.
In 2008, Kirsty Gallacher presented the new version of Gladiators on Sky1 alongside Ian Wright. She did not return for the second series. On 30 August 2008, Kirsty Gallacher appeared on Who Wants to Be a Millionaire? with Duncan Bannatyne. Kirsty Gallacher has also guest presented GMTV with Lorraine in August 2010 for two weeks and Lorraine on ITV Breakfast.
In May 2011, Kirsty Gallacher returned to Sky Sports to present for Sky Sports News. On 27 August 2015, it was confirmed that Kirsty Gallacher would be taking part in the 2015 series of Strictly Come Dancing. On 5 September 2015, it was announced Kirsty Gallacher would be paired with professional dancer Brendan Cole for the series.