In 2004 Charlotte Jackson wrote and presented sports news for a variety of sports websites, including sportal.com, TEAMtalk, Football365 and Golf365 among other sports related websites where she wrote and presented sports bulletins. Jackson also presented the coverage of the National Hunt Festival for the official Cheltenham website in 2006. Charlotte Jackson joined Setanta Sports News in 2007, co-hosting Lunchtime Live alongside Murray Dron, and presented various live events, including BetFred League of Legends darts tournament.
She presented the Beijing Bulletin for Al Jazeera +3 Sport’s coverage of the 2008 Summer Olympics, with Rhodri Williams. After the channel ceased broadcasting in June 2009, she joined Sky Sports in August 2009, presenting on Sky Sports News. She also regularly appears with Tim Shaw on his radio show, Absolution. She hosted the 2009 FIFA World Player of the Year Awards Ceremony in Zurich alongside Pedro Pinto She appeared as a reporter in the Keith Lemon film.
Charlotte Jackson presented Sky Sports Football quiz show Take it Like a Fan with John Fendley. The show is based on going to different British football league grounds and asking quiz questions. Charlotte Jackson also presented the second series of ITV’s 71 Degrees North alongside Paddy McGuinness, and was team captain for the girls for ITV’s The Big Quiz Sports Special. In 2013, Charlotte Jackson was a contestant in ITV’s celebrity diving show Splash!, where she reached the semi-finals, despite breaking a toe.