Charlotte Hawkins began her broadcasting career with ITN in 1999 as a news reader and reporter for LBC Radio. She was one of the first journalists at the fatal Paddington rail crash and provided live reports from the scene. In January 2000, Charlotte Hawkins moved to ITV Meridian in the southeast, and co-presented the hour-long current affairs series The Big Story.
Charlotte Hawkins presented several stints on Five News, in the absence of stand-in Matt Barbet who was providing maternity leave cover for main presenter Natasha Kaplinsky, for a period in 2010. In 2010, she was an occasional guest news reviewer on the ITV programme This Morning.
On 3 March 2014 it was announced Charlotte Hawkins would become a presenter on the new ITV Breakfast programme Good Morning Britain. She made her last appearance on Sky News Sunrise on 6 March 2014 and made her debut on Good Morning Britain on 28 April 2014, where she currently co-hosts the show with Ben Shephard, Sean Fletcher and Susanna Reid from 6 to 8.30am, every day except Thursdays.